PEAQ-ITC Isothermal Titration Calorimeter

PEAQ-ITC Isothermal Titration Calorimeter

The PEAQ-ITC Isothermal Titration Calorimeter is a state-of-the-art biophysical analysis instrument designed to measure the thermodynamics of molecular interactions with high sensitivity and precision. This system enables researchers to directly quantify binding constants, enthalpy, entropy, and stoichiometry in a label-free and solution-based environment, making it ideal for applications in drug discovery, protein-ligand interactions, antibody characterization, and biomolecular research.

With its intuitive software and robust experimental design, the PEAQ-ITC allows fast, reproducible, and highly accurate measurements, reducing experimental complexity and enhancing data reliability.

Key Features

1. High-Sensitivity Calorimetric Detection
Capable of detecting minute heat changes, enabling analysis of low-affinity interactions and small sample volumes.

2. Label-Free, Solution-Based Measurements
Eliminates the need for fluorescent or radioactive labels, preserving native molecular behavior.

3. Comprehensive Thermodynamic Analysis
Provides full characterization of interactions, including binding affinity (K_d), enthalpy (ΔH), entropy (ΔS), and stoichiometry (n).

4. User-Friendly Software Interface
Automated experimental setup, real-time data monitoring, and advanced data fitting options for simplified operation.

5. Low Sample Consumption
Optimized cell design and injection protocols minimize protein or ligand usage without compromising accuracy.

6. Wide Application Range
Suitable for studying protein-protein, protein-ligand, protein-DNA, and antibody-antigen interactions.

Typical Applications

Drug discovery and small molecule screening

Protein-ligand interaction characterization

Antibody and biotherapeutic binding studies

Protein-protein and protein-DNA interaction analysis

Enzyme kinetics and inhibitor studies

Advantages for Laboratories

Highly reproducible, quantitative thermodynamic data

Reduces experimental preparation and complexity

Supports broad range of molecular interactions

Facilitates critical decision-making in research and development

The PEAQ-ITC Isothermal Titration Calorimeter combines cutting-edge calorimetric technology with intuitive operation, providing an essential platform for accurate and comprehensive characterization of biomolecular interactions in research and pharmaceutical development.